Anti-Navbeta2 Na+ Channel Antibody

ArtNr	75-379
Hersteller	Antibodies Incorporated
Menge	100 uL
Kategorie	Neuroscience Neural Lineage Markers Antibodies Immunohistochemistry Immunocytochemistry Primary Antibodies Immunoblot Neurodegeneration Markers
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, IHC, ICC
Clon	N395/68
Specific against	Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG2b
Konjugat/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Sodium channel subunit beta-2
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Primary Antibody
Manufacturer - Targets	Navbeta2 Na+ channel
Country of Origin	United States
Shipping Temperature	Shipped on ice packs
Storage Conditions	Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Molecular Weight	40 kDa
Manufacturer - Research Area	Ion Channels and Modulators, Na+ Channels
Expiration	24 months from date of receipt
Immunogen	Fusion protein amino acids 1-215 (full-length) of mouse Navbeta2 (accession number Q56A07) produced recombinantly in E. Coli
Immunogen Species	Mouse
Description	Our Anti-Navbeta2 Na+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N395/68. It is KO validated, detects mouse and rat Navbeta2 Na+ channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.
Target Description	Sodium channel subunit beta-2 or Navbeta2 Na+ channel is encoded by SCN2B. Voltage gated sodium channels are made up of an alpha (pore forming) subunit and 1 or 2 beta subunits. Navß2 is a transmembrane protein and acts as a regulatory subunit in excitable membranes and modulates the kinetics of channel. Nabß2 is expressed in many tissues, including the central and peripheral nervous system, heart, and skeletal muscle. Diseases associated with this gene include Familial Atrial Fibrillation
Clonality	Monoclonal
Manufacturer - Specificity	Does not cross-react with Navbeta1, Navbeta3 or Navbeta4 (based on KO validation results)
Concentration	1 mg/mL
Form	Purified by Protein A chromatography
Buffer	10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125
Production Notes	Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
Quality Control	Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
Quality Control: Application	WB Brain
Usage Statement	These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Manufacturer - Statement	We produce our Navbeta2 Na+ channel mouse monoclonal primary antibody from hybridoma clone N395/68. It is great in IHC, ICC, WB and is purified by Protein A chromatography.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 uL

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Lieferung vsl. bis 28.08.2025

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