Anti-NR2A Glutamate Receptor Antibody

NR2A glutamate receptor

Shipped on ice packs

170 kDa

24 months from date of receipt

Rat

Glutamate receptor NMDA2A or GluN2A/NR2A glutamate receptor is a member of the glutamate-gated ion channel family. NR2A is a subunit of the ligand-gated ion channel with high calcium permeability and voltage-dependent sensitivity to magnesium. NR2A is expressed throughout the brain, including striatum, forbrain, cerebellum (at protein level) brain cortex, piriform cortex, hippocampus, caudate-putamen, dentate gyrus and granule cell layer. It is found at the postsynaptic cell membrane, dendritic spine, synapse, and cytoplasmic vesicle membrane. A variety of neurological diseases, including epilepsy, intellectual disability, autism spectrum disorders, developmental delay, and schizophrenia are associated with mutations in the NR2A gene.

Does not cross-react with NR2B

TC Supernatant

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

ICC

We produce our NR2A glutamate receptor mouse monoclonal primary antibody from hybridoma clone N327A/38. It is great in IHC, ICC, WB and is TC supernatant.