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Anti-IP3 Receptor, Type 1 Antibody

Anti-IP3 Receptor, Type 1 Antibody

ArtNr	75-035
Hersteller	Antibodies Incorporated
Menge	100 uL
Kategorie	Neuroscience Molecular Targets for Neuroscience Antibodies Immunohistochemistry Immunoprecipitation Primary Antibodies Immunoblot
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, IP, IHC, ICC
Clon	L24/18
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Dog (Canine, Canis lupus familiaris)
Host	Mouse
Isotype	IgG1
Konjugat/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Inositol 1,4,5-trisphosphate receptor type 1 (IP3 receptor isoform 1) (IP-3-R) (IP3R 1) (InsP3R1) (Type 1 inositol 1,4,5-trisphosphate receptor) (Type 1 InsP3 receptor)
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Primary Antibody
Manufacturer - Targets	IP3 receptor, type 1
Country of Origin	United States
Shipping Temperature	Shipped on ice packs
Storage Conditions	Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Molecular Weight	300 kDa (varies due to glycosylation)
Manufacturer - Research Area	Ion Channels and Modulators, Other Ion Channels
Expiration	24 months from date of receipt
Immunogen	Fusion protein amino acids 2680-2749 (cytoplasmic carboxyl terminus) of rat type 1 IP3R (accession number P29994) produced recombinantly in E. Coli
Immunogen Species	Rat
Target Description	Inositol 1, 4, 5-trisphosphate receptor type 1 or IP3 receptor type 1 (IP3R1) serves as a receptor for IP3. It is expressed in many tissues in the endoplasmic reticulum to facilitate calcium release from the ER. In brain, (IP3R1) is predominantly expressed in cerebellar Purkinje neurons.. Mutations in this gene cause spinocerebellar ataxia type 15 and spinocerebellar Ataxia 29.
Clonality	Monoclonal
Manufacturer - Specificity	Does not recognize type 2 and type 3 IP3R’s
Concentration	1 mg/mL
Form	Purified by Protein A chromatography
Buffer	10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.4
Production Notes	Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
Quality Control	Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
Quality Control: Application	WB Brain
Dilution Range: WB	1:1000
Dilution Range: IHC	1:100
Dilution Range: ICC	1:100
Usage Statement	These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Manufacturer - Statement	We produce our IP3 receptor, type 1 mouse monoclonal primary antibody from hybridoma clone L24/18. It is great in IHC, ICC, IP, WB and is purified by Protein A chromatography.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 uL

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Lieferung vsl. bis 28.08.2025

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