Anti-Neuroligin-1 Antibody

Neuroligin-1

Shipped on ice packs

120 kDa

24 months from date of receipt

Rat

Neuroligin 1 is a member of a large family of alternatively sliced proteins located at the post synaptic surface in the central nervous system, and stains as a post synaptic marker. Neuroligin 1 is involved in cell-cell-interactions by binding to neurexin family members and other postsynaptic proteins to localize receptors and channels in the postsynaptic density. Suggested roles for Neuroligin 1 include synapse function and synaptic signal transmission and maintaining synapse integrity. Mutations in Neuroligans have been implicated in autism and other cognitive disorders.

Does not cross-react with Neuroligin-2, -3, -4 or -4*

Purified by Protein A chromatography

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

WB Brain

1:500

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.