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Anti-Nav1.8 Na+ Channel Antibody

Anti-Nav1.8 Na+ Channel Antibody

ArtNr	75-166
Hersteller	Antibodies Incorporated
Menge	100 uL
Kategorie	Neuroscience Molecular Targets for Neuroscience Antibodies Immunohistochemistry Immunocytochemistry Primary Antibodies Immunoblot
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, IHC, ICC
Clon	N134/12
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG2a
Konjugat/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Sodium channel protein type 10 subunit alpha (Peripheral nerve sodium channel 3) (PN3) (Sensory neuron sodium channel) (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8)
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Primary Antibody
Manufacturer - Targets	Nav1.8 Na+ channel
Country of Origin	United States
Shipping Temperature	Shipped on ice packs
Storage Conditions	Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Molecular Weight	220 kDa
Manufacturer - Research Area	Ion Channels and Modulators, Na+ Channels
Expiration	24 months from date of receipt
Immunogen	Fusion protein amino acids 1724-1956 (cytoplasmic C-terminus) of rat Nav1.8 (accession number Q62968) produced recombinantly in E. Coli
Immunogen Species	Rat
Description	Our Anti-Nav1.8 Na+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N134/12. It is KO validated, detects human, mouse, and rat Nav1.8 Na+ channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.
Target Description	NAV1.8 is a member of the voltage-gated sodium channel family, which function in producing and propagating action potentials. Sodium channels are composed of a large alpha subunit that may be associated with one or more smaller beta subunits. Nav 1.8 is an integral membrane glycoprotein that is responsible for the initial rising phase of action in most excitable cells. Nav 1.8 is expressed in neurons in the dorsal root ganglion (DRG). and appears to have a role in pain pathways.
Clonality	Monoclonal
Manufacturer - Specificity	Does not react with Nav1.7
Concentration	1 mg/mL
Form	Purified by Protein A chromatography
Buffer	10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.93
Production Notes	Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
Quality Control	Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.
Quality Control: Application	ICC
Dilution Range: WB	1:1000
Dilution Range: IHC	1:250
Dilution Range: ICC	1:250
Usage Statement	These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Manufacturer - Statement	We produce our Nav1.8 Na+ channel mouse monoclonal primary antibody from hybridoma clone N134/12. It is great in IHC, ICC, WB and is purified by Protein A chromatography.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 uL

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Lieferung vsl. bis 11.09.2025

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