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Anti-Kir2.1 K+ Channel Antibody

Anti-Kir2.1 K+ Channel Antibody

ArtNr	75-210
Hersteller	Antibodies Incorporated
Menge	100 uL
Kategorie	Antibodies Immunocytochemistry Primary Antibodies Immunoblot
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, IHC, ICC
Clon	N112B/14
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG1
Konjugat/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Inward rectifier potassium channel 2 (Inward rectifier K(+) channel Kir2.1) (IRK-1) (Potassium channel, inwardly rectifying subfamily J member 2)
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Primary Antibody
Manufacturer - Targets	Kir2.1 K+ channel
Country of Origin	United States
Shipping Temperature	Shipped on ice packs
Storage Conditions	Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Molecular Weight	55 kDa
Manufacturer - Research Area	Ion Channels and Modulators, K+ Channels
Expiration	24 months from date of receipt
Immunogen	Synthetic peptide amino acids 390-411 (cytoplasmic C-terminus) of mouse Kir2.1 (accession number P35561)
Immunogen Species	Mouse
Description	Our Anti-Kir2.1 K+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N112B/14. It detects mouse and rat Kir2.1 K+ channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.
Target Description	Kir2.1 (KCNJ2) is a member of the inward rectifier potassium ion channel family which also includes Kir2.2 and Kir2.3. Kir2.1 is expressed in the membranes of many tissues, including heart, skeletal muscle, kidney and diffusely distributed throughout the brain. Kir2.1 has a role in cardiac excitability and has been shown to have interactions with CLG4, Interleukin 16 and TRAK2. Defects in Kir2.1 are involved with the diseases long QT syndrome type 7 (also known as andersen-Tawil syndrome), short QT syndrome 3, and Familial Atrial Fibrillation 9.
Clonality	Monoclonal
Manufacturer - Specificity	No cross-reactivity against Kir2.2 or Kir2.3
Concentration	1 mg/mL
Form	Purified by Protein A chromatography
Buffer	10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125
Production Notes	Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
Quality Control	Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.
Quality Control: Application	ICC
Usage Statement	These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Manufacturer - Statement	We produce our Kir2.1 K+ channel mouse monoclonal primary antibody from hybridoma clone N112B/14. It is great in IHC, ICC, WB and is purified by Protein A chromatography.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 uL

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Lieferung vsl. bis 11.09.2025

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