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Anti-MMACHC Antibody

ArtNr 75-239
Hersteller Antibodies Incorporated
Menge 100 uL
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB, ICC
Clon N230/21
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Mouse
Isotype IgG1
Konjugat/Tag Unconjugated
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Methylmalonic aciduria and homocystinuria type C protein (EC 1.16.1.-) (CblC) (Cyanocobalamin reductase (cyanide-eliminating))
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Primary Antibody
Manufacturer - Targets
MMACHC
Country of Origin
United States
Shipping Temperature
Shipped on ice packs
Storage Conditions
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Molecular Weight
32 kDa
Manufacturer - Research Area
Rare Diseases
Expiration
24 months from date of receipt
Immunogen
Fusion protein amino acids 1-282 (full-length) of human MMACHC (accession number Q9Y4U1) produced recombinantly in E. Coli
Immunogen Species
Human
Description
Our Anti-MMACHC mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N230/21. It detects human and mouse MMACHC, and is purified by Protein A chromatography. It is great for use in ICC, WB.
Target Description
Metabolism of Cobalamin Associated C is encoded by the gene MMACHC. MMACHC is a member of the MMACHC family. MMACHC may have a role in the binding and intracellular trafficking of of cobalamin. MMACHC is widely expressed with higher levels in the liver, spleen, lymph nodes, thymus, and bone marrow. Diseases associated with MMACHC include Methylmalonic Aciduria and Homocystinuria, Cblc Type and Methylmalonic Acidemia with Homocystinuria.
Clonality
Monoclonal
Manufacturer - Specificity
No cross-reactivity reported
Concentration
1 mg/mL
Form
Purified by Protein A chromatography
Buffer
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125
Production Notes
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
Quality Control
Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.
Quality Control: Application
ICC
Usage Statement
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Manufacturer - Statement
We produce our MMACHC mouse monoclonal primary antibody from hybridoma clone N230/21. It is great in ICC, WB and is purified by Protein A chromatography.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 uL
Lieferbar: In stock
lieferbar

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