Vergleich

Anti-Alpha-2C Adrenergic Receptor Antibody

ArtNr 75-300
Hersteller Antibodies Incorporated
Menge 100 uL
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB, ICC
Clon N330A/51
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Mouse
Isotype IgG2a
Konjugat/Tag Unconjugated
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Alpha-2C adrenergic receptor (Alpha-2 adrenergic receptor subtype C4) (Alpha-2C adrenoreceptor) (Alpha-2C adrenoceptor) (Alpha-2CAR)
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Primary Antibody
Manufacturer - Targets
Alpha-2C adrenergic receptor
Country of Origin
United States
Shipping Temperature
Shipped on ice packs
Storage Conditions
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Molecular Weight
50 kDa and larger (possibly due to dimerization)
Manufacturer - Research Area
Neurotransmitter Receptors
Expiration
24 months from date of receipt
Immunogen
Synthetic peptide amino acids 442-462 (QDFRRSFKHILFRRRRRGFRQ, cytoplasmic C-terminus) of human Alpha-2C adrenergic receptor (accession number P18825)
Immunogen Species
Human
Description
Our Anti-Alpha-2C adrenergic receptor mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N330A/51. It is KO validated, detects human and mouse Alpha-2C adrenergic receptor, and is purified by Protein A chromatography. It is great for use in ICC, WB.
Target Description
α-2C adrenergic receptor or α-2 Adrenergic Receptor Subtype C4 is encoded by the gene ADRA2C. It belongs to the Adrenergic receptor subfamily of G-protein coupled receptors. α-2C adrenergic receptors mediate catecholamine-induced inhibition of adenylate cyclase by the action of G proteins. α-2C adrenergic is involved in the regulation of neurotransmitter release from sympathetic nerves and adrenergic neurons. α-2C adrenergic receptors are expressed in brain, kidney and heart. Diseases associated with ADRA2C include Raynaud Phenomenon.
Clonality
Monoclonal
Manufacturer - Specificity
Does not cross-react with other adrenergic receptors (based on KO validation results)
Concentration
1 mg/mL
Form
Purified by Protein A chromatography
Buffer
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125
Production Notes
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
Quality Control
Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.
Quality Control: Application
ICC
Usage Statement
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Manufacturer - Statement
We produce our Alpha-2C adrenergic receptor mouse monoclonal primary antibody from hybridoma clone N330A/51. It is great in ICC, WB and is purified by Protein A chromatography.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 uL
Lieferbar: In stock
lieferbar

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