ACTL6A Antibody

ArtNr	OAAN01251-100UL
Hersteller	AVIVA Systems Biology
Menge	100 ul
Kategorie	Antibodies Immunohistochemistry Immunoprecipitation Western Blot Immunofluorescence Primary Antibodies CHiP
Format	Liquid
Applikationen	WB, IF, IP, IHC, CHIP
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Alias	Arp4,ACTL6,BAF53A,INO80K,ARPN-BETA
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	47 kDa
Manufacturer - Application Additional Information	WB: 1:500 - 1:2, 000. IHC: 1:50 - 1:200. IF: 1:50 - 1:200. IP: 1:50 - 1:200. CHIP: 1:20 - 1:100
Gene symbol	ACTL6A
Gene Fullname	actin like 6A
Product format	Liquid
Reconstitution and storage	Store at -20C. Avoid repeated freeze/thaw cycles.
Description of target	This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described.
Nucleotide accession_num	NM_004301.4
Protein accession_num	NP_004292.1
Protein name	Actin-like protein 6A
Clonality	Polyclonal
Purification	Affinity purified against immunogen
Immunogen	Recombinant protein of human ACTL6A
Storage Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

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Menge: 100 ul

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