MAP1LC3A Antibody

ArtNr	OACA06266-100UG
Hersteller	AVIVA Systems Biology
Menge	100 ug
Kategorie	Neuroscience Neural Lineage Markers Protein Aggregation, Clearance & Misfolding Antibodies Cell Biology Cell Status Flow Cytometry Immunohistochemistry Western Blot ELISA Immunocytochemistry Autophagy Primary Antibodies Immunostaining Oligodendrocyte Markers Astroglia Markers
Format	Liquid
Applikationen	IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Citations	[1]"The Legionella effector RavZ inhibits host autophagy through irreversible Atg8 deconjugation." Choy A., Dancourt J., Mugo B., O'Connor T.J., Isberg R.R., Melia T.J., Roy C.R. Science 338:1072-1076(2011). [2]"DOR/Tp53inp2 and Tp53inp1 constitute a metazoan gene family encoding dual regulators of autophagy and transcription." Sancho A., Duran J., Garcia-Espana A., Mauvezin C., Alemu E.A., Lamark T., Macias M.J., Desalle R., Royo M., Sala D., Chicote J.U., Palacin M., Johansen T., Zorzano A. PLoS ONE 7:E34034-E34034(2011). [3]"Rab GTPase-activating proteins in autophagy: regulation of endocytic and autophagy pathways by direct binding to human ATG8 modifiers." Popovic D., Akutsu M., Novak I., Harper J.W., Behrends C., Dikic I. Mol. Cell. Biol. 32:1733-1744(2011).
Alias	ATG8E;Autophagy-related protein LC3 A;autophagy-related ubiquitin-like modifier LC3 A;LC3;LC3A;MAP1 light chain 3-like protein 1;MAP1A/1B light chain 3 A;MAP1A/MAP1B LC3 A;MAP1A/MAP1B light chain 3 A;MAP1ALC3;MAP1BLC3;Microtubule-associated protein 1 light chain 3 alpha;microtubule-associated proteins 1A/1B light chain 3;microtubule-associated proteins 1A/1B light chain 3A.
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Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Gene symbol	MAP1LC3A
Gene Fullname	microtubule associated protein 1 light chain 3 alpha
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes) (PubMed:20713600, PubMed:24290141). Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (PubMed:20713600).
Nucleotide accession_num	NM_032514
Protein accession_num	NP_115903
Protein name	Microtubule-associated proteins 1A/1B light chain 3A
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human Microtubule-associated proteins 1A/1B light chain 3A protein (1-120AA)

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Menge: 100 ug

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Lieferung vsl. bis 13.11.2025

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