TDP1 Antibody

ArtNr	OACD00442-1ML
Hersteller	AVIVA Systems Biology
Menge	1 ml
Kategorie	Antibodies Immunohistochemistry Immunoprecipitation Western Blot ELISA Immunocytochemistry Cardiovascular Research Thrombosis & Hemostasis Primary Antibodies Immunochemistry
Format	Liquid
Applikationen	WB, IP, IHC, ICC
Specific against	Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Alias	Protein expressed in male leptotene and zygotene spermatocytes 501.
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Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Molecular Weight	69 kDa
Application Data	Western blotting: 1:50-400 Immunocytochemistry in formalin fixed cells: 1:50-500 Immunohistochemistry in formalin fixed frozen section: 1:50-500 Immunohistochemistry in paraffin section: 1:10-100 Enzyme-linked Immunosorbent Assay: 1:100-1:5, 000 Optimal working dilutions must be determined by end user.
Gene symbol	TDP1
Gene Fullname	Tyrosyl DNA Phosphodiesterase 1
Product format	Liquid. PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Reconstitution and storage	2°C to 8°C\|-20°C
Description of target	DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 3'-phosphodiester bond, giving rise to DNA with a free 3' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase I active site tyrosine residue. Hydrolyzes 3'-phosphoglycolates on protruding 3' ends on DNA double-strand breaks due to DNA damage by radiation and free radicals. Acts on blunt-ended double-strand DNA breaks and on single-stranded DNA. Has low 3'exonuclease activity and can remove a single nucleoside from the 3'end of DNA and RNA molecules with 3'hydroxyl groups. Has no exonuclease activity towards DNA or RNA with a 3'phosphate (By similarity).
Protein name	Tyrosyl-DNA phosphodiesterase 1
Clonality	Polyclonal
Purification	Affinity Purified; Protein A Purified
Immunogen	Range: Glu4 - Gln215
Manufacturer - Specificity	The antibody is a rabbit polyclonal antibody raised against TDP1. It has been selected for its ability to recognize TDP1 in immunohistochemical staining and western blotting.
Concentration	0.5 mg/ml

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OACD00442-1ML-datasheet.pdf

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Menge: 1 ml

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Lieferung vsl. bis 25.12.2025

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