FLNA Antibody

ArtNr	OACD03575-1ML
Hersteller	AVIVA Systems Biology
Menge	1 ml
Kategorie	Oncology Antibodies By Cell Type Hematology Lymphoma Myeloma Immunohistochemistry Immunoprecipitation Western Blot ELISA Immunocytochemistry Cardiovascular Research Thrombosis & Hemostasis Atherosclerosis Primary Antibodies Immunochemistry
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IP, IHC, ICC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ABP-280;ABPX;actin binding protein 280;Actin-binding protein 280;alpha-filamin;CSBS;CVD1;endothelial actin-binding protein;epididymis secretory sperm binding protein;FGS2;filamin A,alpha;filamin-1;filamin-A;FLN;FLN1;FLN-A;FMD;MNS;NHBP;non-muscle filamin;OPD;OPD1;OPD2;XLVD;XMVD.
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Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Molecular Weight	280 kDa
Application Data	Western blotting: 1:50-400 Immunocytochemistry in formalin fixed cells: 1:50-500 Immunohistochemistry in formalin fixed frozen section: 1:50-500 Immunohistochemistry in paraffin section: 1:10-100 Enzyme-linked Immunosorbent Assay: 1:100-1:5, 000 Optimal working dilutions must be determined by end user.
Gene symbol	FLNA
Gene Fullname	filamin A
Product format	Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Reconstitution and storage	2°C to 8°C\|-20°C
Description of target	Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface-localized furin, modulates its rate of internalization and directs its intracellular trafficking (By similarity). Involved in ciliogenesis. Plays a role in cell-cell contacts and adherens junctions during the development of blood vessels, heart and brain organs. Plays a role in platelets morphology through interaction with SYK that regulates ITAM- and ITAM-like-containing receptor signaling, resulting in by platelet cytoskeleton organization maintenance (By similarity).
Nucleotide accession_num	NM_001110556
Protein accession_num	NP_001104026.1
Protein name	Filamin-A
Clonality	Polyclonal
Purification	Affinity Purified; Protein A Purified
Immunogen	Range: Ser2 - Pro274
Manufacturer - Specificity	The antibody is a rabbit polyclonal antibody raised against FLNa. It has been selected for its ability to recognize FLNa in immunohistochemical staining and western blotting.
Concentration	0.5 mg/ml

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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OACD03575-1ML-datasheet.pdf

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Menge: 1 ml

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Lieferung vsl. bis 25.12.2025

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