VEGFA Antibody

ArtNr	OACD08194-1ML
Hersteller	AVIVA Systems Biology
Menge	1 ml
Kategorie	Oncology Food Safety Allergenes Neuroscience Molecular Targets for Neuroscience Neural Development Antibodies By Cell Type Blastoma Carcinoma Hematology Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Movement Cell Adhesion Cell Culture Cytokines Adenocarcinoma Immunohistochemistry Immunoprecipitation Western Blot ELISA Immunocytochemistry Primary Antibodies By Organ Bladder Cancer Immunochemistry
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IP, IHC, ICC
Specific against	Human (Homo sapiens), Pig (Porcine, Sus scrofa domesticus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	MVCD1;vascular endothelial growth factor A;vascular endothelial growth factor A121;vascular endothelial growth factor A165;vascular permeability factor;VEGF;VPF.
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Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Molecular Weight	16 kDa
Application Data	Western blotting: 1:50-400 Immunocytochemistry in formalin fixed cells: 1:50-500 Immunohistochemistry in formalin fixed frozen section: 1:50-500 Immunohistochemistry in paraffin section: 1:10-100 Enzyme-linked Immunosorbent Assay: 1:100-1:5, 000 Optimal working dilutions must be determined by end user.
Gene symbol	VEGFA
Gene Fullname	vascular endothelial growth factor A
Product format	Liquid. 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Reconstitution and storage	2°C to 8°C\|-20°C
Description of target	Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development (By similarity).
Nucleotide accession_num	NM_001025366
Protein accession_num	NP_001020537.2
Protein name	Vascular endothelial growth factor A
Clonality	Polyclonal
Purification	Affinity Purified; Protein A Purified
Immunogen	Range: Pro28 - Arg191
Manufacturer - Specificity	The antibody is a rabbit polyclonal antibody raised against VEGF145. It has been selected for its ability to recognize VEGF145 in immunohistochemical staining and western blotting.
Concentration	0.5 mg/ml

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OACD08194-1ML-datasheet.pdf

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Menge: 1 ml

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Lieferung vsl. bis 25.12.2025

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