DR5 (Fas like protein,Apoptosis inducing protein TRICK2A/2B,Apoptosis inducing receptor TRAIL R2,CD 262,CD262,CD262 antigen,Cytotoxic TRAIL receptor 2,Death domain containing receptor for TRAIL/Apo 2L,Death domain contai

Antibodies / Antibodies-Apoptosis

-20°C

Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 0.1mg/ml BSA, 50% glycerol.

Purified recombinant human TNFRSF10B protein fragments expressed in E. coli.

The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009]

Applications:
Suitable for use in Western Blot and Immunocytochemistry. Other applications not tested.

Recommended Dilution:
Western Blot: 1:500-1:2000
Immunocytochemistry: 1:100
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.