HSP60 (SPG13, GROEL, CPN60, HuCHA60, spastic paraplegia 13 (autosomal dominant), Mitochondrial matrix protein P1, P60 lymphocyte protein, Heat shock protein 60, 60kD chaperonin, Chaperonin 60)

Antibodies / Antibodies-Heat Shock Proteins

4°C/-20°C

Ascites, supplied as a lyophilized powder. Reconstitution: 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.

Recombinant human heat shock protein 60 (HSP60)

Heat shock 60KD protein (HSP60) is a member of the chaperonin class of protein factors and the nuclear encoded mitochondrial HSP60 is required for the assembly into oligomeric complexes of proteins imported into the mitochondrial matrix. HSP60 is linked head to head comprising approximately 17 kb and consist of 12 exons. HSP60 is a self-molecule, it can downregulate adaptive immune responses by upregulating Tregs innately through TLR2 signaling.

UniProt Number:
Human(P10809), Mouse(P63038), Rat(P63039)

Gene ID:
HSPD1

Applications:
Suitable for use in Western Blot, Immunohistochemistry (Paraffin).

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Handling:
Store at -20˚C for one year. After reconstitution, store at 4˚C for one month. Can also be aliquoted and stored frozen at -20˚C for long term.
Avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.