TFB1M (Dimethyladenosine Transferase 1,Mitochondrial,Mitochondrial 12S rRNA Dimethylase 1,Mitochondrial Transcription Factor B1,h-mtTFB,h-mtTFB1,hTFB1M,mtTFB1,S-adenosylmethionine-6-N',N'-adenosyl(rRNA) Dimethyltransfera

Antibodies / Antibodies-Transcription Factors

-20°C

Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.

Synthetic peptide corresponding to 13aa from near the C-terminus of TFB1M. Species sequence homology: canine.

S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity.

Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
ELISA: 1:64, 000
Western Blot: 0.3-1ug/ml
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.