FXR2 (FMR1L2,Fragile X Mental Retardation 1 like 2,Fragile X Mental Retardation Geneautosomal Homolog 2,Fragile X Mental Retardation Syndrome Related Protein 2,FXR 2,FXR2 PEN,Human fragile X Mental Retardation Syndrome R

Antibodies / Antibodies-Disease Markers

-20°C

Supplied as a liquid in PBS, 0.09% sodium azide.

His6-FXR2s fusion protein produced in a bacterial pET system. Species sequence homology: Mouse

FXR2 is a RNA binding protein containing two KH domains and one RCG box which is similar to FMRP and FXR1 It associates with polyribosomes predominantly with 60S large ribosomal subunits It may self-associate or interact with FMRP and FXR1 Fragile X syndrome is caused by the absence of the fragile X mental-retardation protein (FMRP) FMRP is the archetype of a class of cytoplasmic mRNA-binding proteins that includes the fragile X-related 1 and 2 proteins (FXR1 and FXR2) The fragile X-related proteins FXR1 and FXR2 contain a functional nucleolar-targeting signal equivalent to the HIV-1 regulatory proteins

Applications:
Suitable for use in Immunofluorescence, ELISA, Western Blot, Immunoprecipitation, Immunocytochemistry. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Hybridoma:
Sp2/0 myeloma cells with spleen cells from Balb/c mice.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.