ZRSR2(U2 Small Nuclear Ribonucleoprotein Auxiliary Factor 35kD Subunit-Related Protein 2,CCCH Type Zinc Finger,RNA-Binding Motif and Serine/Arginine rich Protein 2,Renal Carcinoma antigen NY-REN-20,U2(RNU2) Small Nuclear

Antibodies / Antibodies-Transcription Factors, Zinc (Ring) Finger

-20°C

Supplied as a liquid in PBS, 0.09% sodium azide.

KLH conjugated synthetic peptide corresponding to aa453-482 at the C-terminal region of human ZRSR2.

Pre-mRNA-binding protein required for splicing of both U2-and U12-type introns. Selectively interacts with the 3'-splice site of U2-and U12-type pre-mRNAs and promotes different steps in U2 and U12 intron splicing. Recruited to U12 pre-mRNAs in an ATP-dependent manner and is required for assembly of the prespliceosome, a precursor to other spliceosomal complexes. For U2-type introns, it is selectively and specifically required for the second step of splicing.

Applications:
Suitable for use in Western Blot, Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Immunohistochemistry(Paraffin): 1:25
Western Blot: 1:1000
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.