SLC29A3, NT (Solute Carrier Family 29 Member 3, Equilibrative Nucleoside Transporter 3, ENT3, HCLAP, HJCD, PHID)

Antibodies / Antibodies-Transport Proteins

-20°C

Supplied as a liquid in PBS, 0.02% sodium azide.

Peptide corresponding to 19aa from human SLC29A3 at N-terminal.

SLC29A3 is a member of the equilibrative nucleoside transporter family which plays a key role in nucleoside and nucleobase uptake for salvage pathways of nucleotide synthesis (1, 2). SLC29A3 is a transmembrane glycoprotein that localizes to the lysosomal membrane and is a broad selectivity, low affinity nucleoside transporter (3). Mutations in the SLC29A3 gene have been associated with H syndrome, which is characterized by cutaneous hyperpigmentation and hypertrichosis, hepatosplenomegaly, heart anomalies, and hypogonadism (4). A related disorder, PHID (pigmented hypertrichosis with insulin-dependent diabetes mellitus), has also been associated with mutations at this locus (5).

Applications:
Suitable for use in Immunofluorescence, ELISA, Western Blot and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Immunofluorescence: 20ug/ml
Western Blot: 1-2ug/ml
Immunohistochemistry (paraffin): 5ug/ml
Optimal dilutions to be determined by the researcher.

Positive Control:
Mouse Bladder Tissue Lysate

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.