Vergleich

Goat Anti-SF3B4 / SAP49 Antibody

ArtNr ABC-AF1983a
Hersteller Abcepta
Menge 100 ug
Kategorie
Typ Antibody Primary
Applikationen WB, ELISA
Specific against other
Host Goat
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products SF3B4, SAP49, Splicing factor 3B subunit 4, Pre-mRNA-splicing factor SF3b 49 kDa subunit, SF3b50, Spliceosome-associated protein 49, SAP 49
Lieferbar
Primary Accession
Q15427
Antigen Type
Synthetic Peptide
Application
WB, E
Bio Background
This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.
Bio References
Many sequence variants affecting diversity of adult human height. Gudbjartsson DF, et al. Nat Genet, 2008 May. PMID 18391951.
Splicing factor 3b subunit 4 binds BMPR-IA and inhibits osteochondral cell differentiation. Watanabe H, et al. J Biol Chem, 2007 Jul 13. PMID 17513295.
Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening. Wu C, et al. Proteomics, 2007 Jun. PMID 17474147.
Large-scale mapping of human protein-protein interactions by mass spectrometry. Ewing RM, et al. Mol Syst Biol, 2007. PMID 17353931.
Human immunodeficiency virus type 1 Vpr induces G2 checkpoint activation by interacting with the splicing factor SAP145. Terada Y, et al. Mol Cell Biol, 2006 Nov. PMID 16923959.
Clonality
Polyclonal
Gene ID
10262
Gene Name
SF3B4
Subtitle
Peptide-affinity purified goat antibody
Reactivity
H
Legend image 1
AF1983a staining (0.1 µg/ml) of Hela lysate (RIPA buffer, 35 µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
Type image 1
WB
Other Accession
NP_005841; 10262; 107701 (mouse);
Predicted
M, Rat, Pig, Dog, Cow
Concentration (mg/ml)
100ug/200ul

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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