GAPDH Antibody

ArtNr	ABC-AM1020b
Hersteller	Abcepta
Menge	400 ul
Kategorie	Neuroscience Metabolism Regulation of Appetite Protein Aggregation, Clearance & Misfolding Antibodies Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies
Typ	Antibody Monoclonal
Applikationen	WB, IF, IHC-P
Clon	1A10A10
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG1
Citations	Inhibition of glyceraldehyde-3-phosphate dehydrogenase activity by antibodies present in the cerebrospinal fluid of patients with multiple sclerosis. Kölln J, et al. J Immunol, 2010 Aug 1. PMID 20610654. Proteome analysis of the thalamus and cerebrospinal fluid reveals glycolysis dysfunction and potential biomarkers candidates for schizophrenia. Martins-de-Souza D, et al. J Psychiatr Res, 2010 May 14. PMID 20471030. Sex-specific proteome differences in the anterior cingulate cortex of schizophrenia. Martins-de-Souza D, et al. J Psychiatr Res, 2010 Apr 8. PMID 20381070. Identification of melanoma antigens using a Serological Proteome Approach (SERPA). Suzuki A, et al. Cancer Genomics Proteomics, 2010 Jan-Feb. PMID 20181627. siah-1 Protein is necessary for high glucose-induced glyceraldehyde-3-phosphate dehydrogenase nuclear accumulation and cell death in Muller cells. Yego EC, et al. J Biol Chem, 2010 Jan 29. PMID 19940145.
NCBI	NP_001243728.1,NP_002037.2
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Glyceraldehyde-3-phosphate dehydrogenase,GAPDH,Peptidyl-cysteine S-nitrosylase GAPDH,2699-,GAPDH,GAPD
Similar products	GAPDH, GAPD, Glyceraldehyde-3-phosphate dehydrogenase, Peptidyl-cysteine S-nitrosylase GAPDH, 2699-
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Manufacturer - Category	Primary Antibodies; Antibody Collections; Cancer; Metabolism; Microbiology; Neuroscience; Signal Transduction; Loading Control
Manufacturer - Targets	GAPDH recombinant protein is used to produce this monoclonal antibody.
Bio Background	The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The enzyme exists as a tetramer of identical chains. Many pseudogenes similar to this locus are present in the human genome.
Clonality	Monoclonal
Gene Name	GAPDH {ECO:0000303\|PubMed:2987855, ECO:0000312\|HGNC:HGNC:4141}
Subtitle	Purified Mouse Monoclonal Antibody (Mab)
Reactivity	H, M, Rat
Calculated Molecular Weight	36053
Antigen Source	HUMAN
Formulation	Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Dilution	WB: 1:1000 IF: 1:25 WB: 1:1000 WB: 1:8000 WB: 1:2000~10000

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