Vergleich

PRDM2 (RIZ1) Antibody

ArtNr ABC-AM1194a-ev
Hersteller Abcepta
Menge 80 ul
Kategorie
Typ Antibody Monoclonal
Applikationen WB, CHIP
Clon 33AT1045
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Mouse
Isotype IgG1
Citations Genotypes and haplotypes of the estrogen receptor genes, but not the retinoblastoma-interacting zinc finger protein 1 gene, are associated with osteoporosis. HarslÞf T, et al. Calcif Tissue Int, 2010 Jul. PMID 20508921.
DNA methylation of the RIZ1 tumor suppressor gene plays an important role in the tumorigenesis of cervical cancer. Cheng HY, et al. Eur J Med Res, 2010 Jan 29. PMID 20159667.
Genetic variants of methyl metabolizing enzymes and epigenetic regulators: associations with promoter CpG island hypermethylation in colorectal cancer. de Vogel S, et al. Cancer Epidemiol Biomarkers Prev, 2009 Nov. PMID 19843671.
Expression of RIZ1 protein (Retinoblastoma-interacting zinc-finger protein 1) in prostate cancer epithelial cells changes with cancer grade progression and is modulated in vitro by DHT and E2. Rossi V, et al. J Cell Physiol, 2009 Dec. PMID 19746436.
RIZ1 is potential CML tumor suppressor that is down-regulated during disease progression. Lakshmikuttyamma A, et al. J Hematol Oncol, 2009 Jul 14. PMID 19602237.
NCBI NP_001007258.1,NP_001129082.1,NP_036363.2,NP_056950.2
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias PR domain zinc finger protein 2,GATA-3-binding protein G3B,Lysine N-methyltransferase 8,MTB-ZF,MTE-binding protein,PR domain-containing protein 2,Retinoblastoma protein-interacting zinc finger protein,Zinc finger protein RIZ,PRDM2,KMT8,RIZ
Similar products PRDM2, KMT8, RIZ, PR domain zinc finger protein 2, GATA-3-binding protein G3B, Lysine N-methyltransferase 8, MTB-ZF, MTE-binding protein, PR domain-containing protein 2, Retinoblastoma protein-interacting zinc finger protein, Zinc finger protein RIZ
Lieferbar
Manufacturer - Category
Primary Antibodies; Cancer; Neuroscience
Manufacturer - Targets
Purified recombinant GST fusion protein encoding aa 1-347 of human RIZ1. This antibody is specific for RIZ1, it does not recognize the isoform beta (RIZ2).
Bio Background
This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene.
Clonality
Monoclonal
Gene Name
PRDM2
Subtitle
Purified Mouse Monoclonal Antibody (Mab)
Reactivity
H, M
Calculated Molecular Weight
188915
Antigen Source
HUMAN
Antigen Region
1-347
Formulation
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Dilution
CHIP: 1:100
CHIP: 1:100
CHIP: 1:100
WB: 1:1000

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 80 ul
Lieferbar: In stock
lieferbar

Vergleichen

Auf den Wunschzettel

Angebot anfordern

Lieferzeit anfragen

Technische Frage stellen

Bulk-Anfrage stellen

Fragen zum Produkt?
 
Schließen