NGFR Antibody

ArtNr	ABC-AM1842a
Hersteller	Abcepta
Menge	400 ul
Kategorie	Oncology Neuroscience Metabolism Diabetes Molecular Targets for Neuroscience Neural Signaling Antibodies By Cell Type Blastoma Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies
Typ	Antibody Monoclonal
Applikationen	WB, IF, IHC-P
Clon	8G3G10
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Mouse
Isotype	IgG2b Kappa
Citations	References for protein: 1. Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271. Boiko AD, et al. Nature, 2010 Jul 1. PMID 20596026. Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls. Schuurhof A, et al. Pediatr Pulmonol, 2010 Jun. 2. Poor replication of candidate genes for major depressive disorder using genome-wide association data. Bosker FJ, et al. Mol Psychiatry, 2010 Mar 30. PMID 20351714. 3. New genetic associations detected in a host response study to hepatitis B vaccine. Davila S, et al. Genes Immun, 2010 Apr. PMID 20237496. 4. Role of the neurotrophin network in eating disorders' subphenotypes: body mass index and age at onset of the disease. Gratacòs M, et al. J Psychiatr Res, 2010 Oct. PMID 20219210. References for SY5Y (SH-SY5Y; ATCC#CRL-2266): 1. Ross RA, et al. Coordinate morphological and biochemical interconversion of human neuroblastoma cells. J. Natl. Cancer Inst. 71: 741-749, 1983. [PubMed: 6137586]; 2. Biedler JL, et al. Multiple neurotransmitter synthesis by human neuroblastoma cell lines and clones. Cancer Res. 38: 3751-3757, 1978. [PubMed: 29704].
NCBI	NP_002498.1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Tumor necrosis factor receptor superfamily member 16,Gp80-LNGFR,Low affinity neurotrophin receptor p75NTR,Low-affinity nerve growth factor receptor,NGF receptor,p75 ICD,CD271,NGFR,TNFRSF16
Similar products	NGFR, TNFRSF16, Tumor necrosis factor receptor superfamily member 16, Gp80-LNGFR, Low affinity neurotrophin receptor p75NTR, Low-affinity nerve growth factor receptor, p75 ICD, NGF receptor, CD271
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Manufacturer - Category	Primary Antibodies; Neuroscience; Signal Transduction
Manufacturer - Targets	This NGFR antibody is generated from mouse immunized with NGFR recombinant protein.
Bio Background	Nerve growth factor receptor contains an extracellular domain containing four 4-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain.
Clonality	Monoclonal
Gene Name	NGFR
Subtitle	Purified Mouse Monoclonal Antibody (Mab)
Reactivity	H, M
Calculated Molecular Weight	45183
Antigen Source	HUMAN
Formulation	Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Dilution	IF: 1:100 WB: 1:500~1000 IHC-P: 1:50~100

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