PDGFR Antibody

Primary Antibodies; Cancer; Cardiovascular; Signal Transduction; Anti-Kinome Antibodies; Lysosome

This gene encodes a cell surface tyrosine kinase receptorfor members of the platelet-derived growth factor family. Thesegrowth factors are mitogens for cells of mesenchymal origin. Theidentity of the growth factor bound to a receptor monomerdetermines whether the functional receptor is a homodimer or aheterodimer, composed of both platelet-derived growth factorreceptor alpha and beta polypeptides. This gene is flanked onchromosome 5 by the genes for granulocyte-macrophagecolony-stimulating factor and macrophage-colony stimulating factorreceptor; all three genes may be implicated in the 5-q syndrome. Atranslocation between chromosomes 5 and 12, that fuses this gene tothat of the translocation, ETV6, leukemia gene, results in chronicmyeloproliferative disorder with eosinophilia. [provided byRefSeq].

PDGFRB

M

HUMAN

WB: 1:8~30

Platelet-derived growth factor receptor beta, PDGF-R-beta, PDGFR-beta, Beta platelet-derived growth factor receptor, Beta-type platelet-derived growth factor receptor, CD140 antigen-like family member B, Platelet-derived growth factor receptor 1, PDGFR-1, CD140b, PDGFRB, PDGFR, PDGFR1