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CTNNB1 Antibody (Ascites)

CTNNB1 Antibody (Ascites)

ArtNr	ABC-AM2074a
Hersteller	Abcepta
Menge	100 ul
Kategorie	Oncology Neuroscience Neural Adhesion Molecules Antibodies By Cell Type Blastoma Carcinoma Hematology Leukemia Adenocarcinoma Western Blot Primary Antibodies
Typ	Antibody Monoclonal
Applikationen	WB
Clon	516CT4.3.3
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgM
Citations	Huang, W., et al. Mol. Cell. Biol. 30(19):4575-4594(2010) Chairoungdua, A., et al. J. Cell Biol. 190(6):1079-1091(2010) Mirza, M.K., et al. J. Exp. Med. 207(8):1675-1685(2010) Guo, Q., et al. Acta Biochim. Biophys. Sin. (Shanghai) 42(7):450-456(2010) Teng, Y., et al. Zhonghua Yi Xue Za Zhi 90(14):988-992(2010)
NCBI	NP_001091679.1,NP_001091680.1,NP_001895.1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Catenin beta-1,Beta-catenin,CTNNB1,CTNNB
Similar products	Catenin beta-1, CTNNB1, CTNNB, Beta-catenin
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Manufacturer - Category	Primary Antibodies; Cancer; Cardiovascular; Neuroscience; Signal Transduction; Anti-Wnt-Pathway (plus Lgr5) Antibodies
Manufacturer - Targets	This CTNNB1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 646-673 amino acids from human CTNNB1.
Bio Background	The protein encoded by this gene is part of a complex ofproteins that constitute adherens junctions (AJs). AJs arenecessary for the creation and maintenance of epithelial celllayers by regulating cell growth and adhesion between cells. Theencoded protein also anchors the actin cytoskeleton and may beresponsible for transmitting the contact inhibition signal thatcauses cells to stop dividing once the epithelial sheet iscomplete. Finally, this protein binds to the product of the APCgene, which is mutated in adenomatous polyposis of the colon.Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer.Three transcript variants encoding the same protein have been foundfor this gene.
Clonality	Monoclonal
Gene Name	CTNNB1
Subtitle	Mouse Monoclonal Antibody (Mab)
Reactivity	H
Predicted Reactivity	Dr, B, Zf, M, Rat, X
Calculated Molecular Weight	85497
Antigen Source	HUMAN
Antigen Region	646-673
Formulation	Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
Dilution	WB: 1:200~1600
Antigen Type	Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 ul

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