BAX Antibody

ArtNr	ABC-AM2087b-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Oncology Antibodies By Cell Type Carcinoma Hematology Lymphoma Cell Biology Cell Status Apoptosis Western Blot Primary Antibodies
Typ	Antibody Monoclonal
Applikationen	WB
Clon	557CT5.2.1
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2b
Citations	Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Montessuit, S., et al. Cell 142(6):889-901(2010) Ding, J., et al. J. Biol. Chem. 285(37):28749-28763(2010) Ho-Pun-Cheung, A., et al. Pharmacogenomics J. (2010) In press: Yu, D.K., et al. Zhonghua Zhong Liu Za Zhi 32(5):324-327(2010)
NCBI	NP_004315.1,NP_620116.1,NP_620118.1,NP_620119.2
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Apoptosis regulator BAX,Bcl-2-like protein 4,Bcl2-L-4,BAX,BCL2L4
Similar products	BAX, BCL2L4, Apoptosis regulator BAX, Bcl-2-like protein 4, Bcl2-L-4
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Manufacturer - Category	Primary Antibodies; Antibody Collections; Cancer; Cell Biology; Metabolism; Amyotrophic Lateral Sclerosis (ALS); Viral process; Host-virus interaction; Apoptosis; Apoptosis signaling; Mitochondrion
Manufacturer - Targets	This BAX antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 28-56 amino acids from human BAX.
Bio Background	The protein encoded by this gene belongs to the BCL2protein family. BCL2 family members form hetero- or homodimers andact as anti- or pro-apoptotic regulators that are involved in awide variety of cellular activities. This protein forms aheterodimer with BCL2, and functions as an apoptotic activator.This protein is reported to interact with, and increase the openingof, the mitochondrial voltage-dependent anion channel (VDAC), whichleads to the loss in membrane potential and the release ofcytochrome c. The expression of this gene is regulated by the tumorsuppressor P53 and has been shown to be involved in P53-mediatedapoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.
Clonality	Monoclonal
Gene Name	BAX
Subtitle	Mouse Monoclonal Antibody (Mab)
Reactivity	H
Calculated Molecular Weight	21184
Antigen Source	HUMAN
Antigen Region	28-56
Formulation	Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Dilution	WB: 1:100
Antigen Type	Synthetic Peptide

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Menge: 80 ul

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