Bio Background |
Neuronal CDC2-like kinase, which is involved in the regulation of neuronal differentiation, is composed of a catalytic subunit, CDK5, and an activating subunit, p25NCK5A. The protein encoded by this gene binds to p25NCK5A and therefore may be involved in neuronal differentiation. The encoded protein may also be a substrate of neuronal CDC2-like kinase. Multiple transcript variants exist for this gene, but the full-length nature of only two has been determined. |
Bio References |
Ichikawa, S., et al. J. Bone Miner. Res. 25(8):1821-1829(2010) Wang, Z., et al. J. Biol. Chem. 285(29):22658-22665(2010) Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010) Lee, S., et al. Cell Cycle 9(4):774-783(2010) Barber, M.J., et al. PLoS ONE 5 (3), E9763 (2010) |