COMT Antibody (N-term) (Ascites)

Primary Antibodies; Metabolism; Neuroscience; Signal Transduction; SARS druggable targets; SARS CoV2 PPIs; AIDS Disease Progression; Infection

Catechol-O-methyltransferase catalyzes the transfer of amethyl group from S-adenosylmethionine to catecholamines, includingthe neurotransmitters dopamine, epinephrine, and norepinephrine.This O-methylation results in one of the major degradative pathwaysof the catecholamine transmitters. In addition to its role in themetabolism of endogenous substances, COMT is important in themetabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms intissues, a soluble form (S-COMT) and a membrane-bound form(MB-COMT). The differences between S-COMT and MB-COMT reside withinthe N-termini. Several transcript variants are formed through theuse of alternative translation initiation sites and promoters.

COMT

H

HUMAN

Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Synthetic Peptide