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FLNA Antibody

ArtNr ABC-AM2240b-ev
Hersteller Abcepta
Menge 80 ul
Kategorie
Typ Antibody Monoclonal
Applikationen WB
Clon 1273CT424.104.153
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Mouse
Isotype IgG1
Citations Gorlin J.B., et al. J. Cell Biol. 111:1089-1105(1990).
Patrosso M.C., et al. Genomics 21:71-76(1994).
Chen E.Y., et al. Hum. Mol. Genet. 5:659-668(1996).
Li J., et al. Mol. Cell. Proteomics 9:2517-2528(2010).
Ota T., et al. Nat. Genet. 36:40-45(2004).
NCBI NP_001104026.1,NP_001447.2
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Filamin-A,FLN-A,Actin-binding protein 280,ABP-280,Alpha-filamin,Endothelial actin-binding protein,Filamin-1,Non-muscle filamin,FLNA,FLN,FLN1
Similar products FLNA, Alpha-filamin, Filamin-1, Endothelial actin-binding protein, Actin-binding protein 280, ABP-280, Non-muscle filamin, FLN, FLN1, Filamin-A, FLN-A
Lieferbar
Manufacturer - Category
Primary Antibodies; Signal Transduction
Manufacturer - Targets
Purified His-tagged FLNA protein was used to produced this monoclonal antibody.
Bio Background
Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface-localized furin, modulates its rate of internalization and directs its intracellular trafficking (By similarity). Involved in ciliogenesis.
Clonality
Monoclonal
Gene Name
FLNA
Subtitle
Mouse Monoclonal Antibody (Mab)
Reactivity
H, M, Rat
Calculated Molecular Weight
280739
Antigen Source
Human
Antigen Region
1-360
Formulation
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Dilution
WB: 1:1000
Antigen Type
Recombinant Protein

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 80 ul
Lieferbar: In stock
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