TYRO3 Antibody

ArtNr	ABC-AM7679B
Hersteller	Abcepta
Menge	400 ul
Kategorie	Oncology Neuroscience Molecular Targets for Neuroscience Antibodies By Cell Type Hematology Leukemia Immunohistochemistry Immunofluorescence Primary Antibodies
Typ	Antibody Monoclonal
Applikationen	IF, IHC-P
Clon	64CT15.6.2.3.1
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Citations	Association study between polymorphims in GAS6-TAM genes and carotid atherosclerosis. Hurtado B, et al. Thromb Haemost, 2010 Sep. PMID 20664904. Protein S controls hypoxic/ischemic blood-brain barrier disruption through the TAM receptor Tyro3 and sphingosine 1-phosphate receptor. Zhu D, et al. Blood, 2010 Jun 10. PMID 20348395. A genomic screen identifies TYRO3 as a MITF regulator in melanoma. Zhu S, et al. Proc Natl Acad Sci U S A, 2009 Oct 6. PMID 19805117. TAM receptor tyrosine kinases: biologic functions, signaling, and potential therapeutic targeting in human cancer. Linger RM, et al. Adv Cancer Res, 2008. PMID 18620092. Toward a confocal subcellular atlas of the human proteome. Barbe L, et al. Mol Cell Proteomics, 2008 Mar. PMID 18029348.
NCBI	NP_006284.2
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Tyrosine-protein kinase receptor TYRO3,Tyrosine-protein kinase BYK,Tyrosine-protein kinase DTK,Tyrosine-protein kinase RSE,Tyrosine-protein kinase SKY,Tyrosine-protein kinase TIF,TYRO3,BYK,DTK,RSE,SKY,TIF
Similar products	TYRO3, SKY, BYK, DTK, RSE, Tyrosine-protein kinase receptor TYRO3, Tyrosine-protein kinase DTK, Tyrosine-protein kinase RSE, Tyrosine-protein kinase SKY, TIF, Tyrosine-protein kinase BYK, Tyrosine-protein kinase TIF
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Manufacturer - Category	Primary Antibodies; Antibody Collections; Cell Biology; Immunology; Neuroscience; Signal Transduction; Anti-Kinome Antibodies; Host cell receptor for virus entry; Viral entry into host cell; Host-virus interaction
Manufacturer - Targets	This TYRO3 Monoclonal antibody is generated from mouse immunized with human recombinant TYRO3 protein.
Bio Background	The gene is part of a 3-member transmembrane receptor kinase receptor family with a processed pseudogene distal on chromosome 15. The encoded protein is activated by the products of the growth arrest-specific gene 6 and protein S genes and is involved in controlling cell survival and proliferation, spermatogenesis, immunoregulation and phagocytosis. The encoded protein has also been identified as a cell entry factor for Ebola and Marburg viruses.
Clonality	Monoclonal
Gene Name	TYRO3
Subtitle	Purified Mouse Monoclonal Antibody (Mab)
Reactivity	H
Calculated Molecular Weight	96905
Antigen Source	HUMAN
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Dilution	IF: 1:10~50 IHC-P: 1:50~100
Antigen Type	Recombinant Protein

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Menge: 400 ul

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