RAB14 Antibody

ArtNr	ABC-AM8601b-ev
Hersteller	Abcepta
Menge	50 ul
Kategorie	Antibodies Cell Biology Cytoskeleton Western Blot Primary Antibodies small GTPases Rab Subfamily
Typ	Antibody Monoclonal
Applikationen	WB
Clon	1779CT692.32.86
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Citations	Proikas-Cezanne T.,et al.Submitted (MAY-1999) to the EMBL/GenBank/DDBJ databases. Ren Y.,et al.Submitted (NOV-1999) to the EMBL/GenBank/DDBJ databases. Huang Y.-P.,et al.Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases. Hu R.-M.,et al.Proc. Natl. Acad. Sci. U.S.A. 97:9543-9548(2000). Bechtel S.,et al.BMC Genomics 8:399-399(2007).
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Ras-related protein Rab-14,RAB14
Similar products	RAB14, Ras-related protein Rab-14
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Manufacturer - Category	Crown Antibodies; Primary Antibodies; Signal Transduction; SARS CoV2 PPIs
Manufacturer - Targets	This RAB14 antibody is generated from a mouse immunized with a recombinant protein of human RAB14.
Bio Background	Involved in membrane trafficking between the Golgi complex and endosomes during early embryonic development. Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development. May act by modulating the kinesin KIF16B-cargo association to endosomes (By similarity). Regulates, together with its guanine nucleotide exchange factor DENND6A, the specific endocytic transport of ADAM1, N- cadherin/CDH2 shedding and cell-cell adhesion.
Clonality	Monoclonal
Gene Name	RAB14
Subtitle	Purified Mouse Monoclonal Antibody (Mab)
Reactivity	H
Predicted Reactivity	C, M
Calculated Molecular Weight	23897
Antigen Source	HUMAN
Formulation	Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Dilution	WB: 1:2000
Antigen Type	Recombinant Protein

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