EIF2A Antibody

ArtNr	ABC-AM8703b
Hersteller	Abcepta
Menge	200 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Applikationen	WB
Specific against	other
Host	Mouse
Isotype	IgG2b kappa
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	EIF2A, EIF2S1, Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit alpha, eIF-2alpha, eIF-2-alpha, eIF-2A
Lieferbar
Primary Accession	P05198
Antigen Type	Recombinant Protein
Application	WB
Bio Background	Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
Bio References	Ernst H., et al.J. Biol. Chem. 262:1206-1212(1987). Langland J.O., et al.Virology 324:419-429(2004). Paytubi S., et al.Biochem. J. 409:223-231(2008). Montero H., et al.J. Virol. 82:1496-1504(2008). Mayya V., et al.Sci. Signal. 2:RA46-RA46(2009).
Clonality	monoclonal
Clone/Animal Names	1763CT191.40.42
Gene ID	1965
Gene Name	EIF2S1 (HGNC:3265)
Subtitle	Purified Mouse Monoclonal Antibody (Mab)
Reactivity	H, M, Rat
Legend image 1	All lanes : Anti-EIF2A Antibody at 1:2000 dilution Lane 1: HepG2 whole cell lysate Lane 2: MCF-7 whole cell lysate Lane 3: PC-12 whole cell lysate Lane 4: NIH/3T3 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 36 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 1	WB
Dilution image 1	1:2000
Isotype	IgG2b, k
Calculated MW	36112
Antigen Source	HUMAN
Target/Specificity	This EIF2A antibody is generated from a mouse immunized with a recombinant protein of human EIF2A.

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Menge: 200 ul

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