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Park7 (DJ-1) Antibody

Park7 (DJ-1) Antibody

ArtNr	ABC-AN1214
Hersteller	Abcepta
Menge	100 ul
Kategorie	Neuroscience Neural Lineage Markers Neuroinflammation Neural Mitochondrial Function Molecular Targets for Neuroscience Targets for Rodent Neurosciences Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding Antibodies Flow Cytometry Western Blot Immunofluorescence Primary Antibodies Glial Cell Markers
Typ	Antibody Monoclonal
Applikationen	WB, FC, IF
Clon	4H4
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Cattle (Bovine)
Host	Mouse
Isotype	IgG1
Citations	Bonifati V, Rizzu P, van Baren MJ, Schaap O, Breedveld GJ, Krieger E, Dekker MC, Squitieri F, Ibanez P, Joosse M, van Dongen JW, Vanacore N, van Swieten JC, Brice A, Meco G, van Duijn CM, Oostra BA, Heutink P. (2003) Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism. Science. Jan 10;299(5604):256-9 Wang Z, Zhang Y, Zhang S, Guo Q, Tan Y, Wang X, Xiong R, Ding J, Chen S. (2011) DJ-1 can inhibit microtubule associated protein 1 B formed aggregates. Mol Neurodegener. Jun 6;6:38
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Protein DJ-1,34--,Contraception-associated protein 1,Protein CAP1,Fertility protein SP22,Parkinson disease protein 7 homolog,Park7,Cap1
Similar products	Protein DJ-1, Cap1, Park7, 34--, Parkinson disease protein 7 homolog, Contraception-associated protein 1, Protein CAP1, Fertility protein SP22
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Manufacturer - Category	Primary Antibodies; Antibody Collections; Cancer; Neuroscience; Signal Transduction; Phospho Antibodies
Manufacturer - Targets	Full length recombinant human Park7 expressed in and purified from E. coli.
Bio Background	Park7, also known as DJ-1, is a member of the peptidase C56 family of proteins and is thought to function as a molecular chaperone. Mutations in park7 have been associated with autosomal recessive, early onset Parkinson’s disease (Bonifati et al., 2003). Recently, park7 has been shown to inhibit microtubule associated protein 1B aggregation thus leading to neuronal apoptosis (Wang et al., 2011).
Clonality	Monoclonal
Gene Name	Park7 {ECO:0000312\|RGD:621808}
Subtitle	Mouse monoclonal antibody
Reactivity	B, H, M, Rat
Calculated Molecular Weight	19974
Antigen Source	human
Formulation	Affinity purified from tissue culture supernatant
Dilution	FC: 1:500 WB: 1:2000 IF: 1:500
Antibody Specificity	Specific for the ~21k park7 protein

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 ul

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