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Lysosomal Associated Membrane Protein 1 (LAMP1) Antibody

Lysosomal Associated Membrane Protein 1 (LAMP1) Antibody

ArtNr	ABC-AN1239
Hersteller	Abcepta
Menge	100 ul
Kategorie	Neuroscience Molecular Targets for Neuroscience Protein Aggregation, Clearance & Misfolding Antibodies Cell Biology Cell Status Western Blot Immunofluorescence Autophagy Primary Antibodies
Typ	Antibody Monoclonal
Applikationen	WB, IF
Clon	5H6
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Cattle (Bovine)
Host	Mouse
Isotype	IgG1
Citations	Makioka K, Yamazaki T, Takatama M, Nakazato Y, Okamoto K. (2012) Activation and alteration of lysosomes in multiple system atrophy. Neuroreport. Mar 28;23(5):270-6.
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Lysosome-associated membrane glycoprotein 1,LAMP-1,Lysosome-associated membrane protein 1,CD107 antigen-like family member A,CD107a,LAMP1
Similar products	LAMP-1, LAMP1, CD107a, Lysosome-associated membrane glycoprotein 1, CD107 antigen-like family member A, Lysosome-associated membrane protein 1
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Manufacturer - Category	Primary Antibodies; Antibody Collections; Cancer; Metabolism; Neuroscience; Signal Transduction; Phospho Antibodies; Host cell receptor for virus entry; Viral entry into host cell; Host-virus interaction; Lysosome
Manufacturer - Targets	Recombinant full length human LAMP1 expressed in and purified from E. coli.
Bio Background	Lysosomal Associated Membrane Protein1 (LAMP1) is a protein that is localized primarily in lysosomes but may also be present on late endosomes and the plasma membrane. LAMP1 antibodies are therefore widely used as lysosome markers. It has recently been suggested that lysosomes are activated in microglia in the progression of multiple system atrophy (MSA) and thus play a key role in its pathology (Makioka et al., 2012).
Clonality	Monoclonal
Gene Name	LAMP1 {ECO:0000303\|PubMed:23632890, ECO:0000312\|HGNC:HGNC:6499}
Subtitle	Mouse monoclonal antibody
Reactivity	B, H, M, Rat
Calculated Molecular Weight	44882
Antigen Source	human
Formulation	Affinity purified from tissue culture supernatant
Dilution	WB: 1:5000 IF: 1:2000
Antibody Specificity	Specific for the ~100k LAMP1 protein.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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