G6PD Antibody

P11413

WB, IHC, FC, E

Monoclonal

G6PD

H

E

Figure 1: Western blot analysis using G6PD mAb against human G6PD (AA: 275-515) recombinant protein.(Expected MW is 53.1 kDa)

1/500 - 1/2000

WB

Figure 3: Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using G6PD mouse mAb with DAB staining.

1/200 - 1/1000

IHC

Figure 5: Flow cytometric analysis of MCF-7 cells using G6PD mouse mAb (green) and negative control (red).

1/200 - 1/400

59257

This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.

Purified recombinant fragment of human G6PD expressed in E. Coli.