AGTR1 Antibody (Center)

Primary Antibodies; Antibody Collections; Cancer; Cardiovascular; Metabolism; Signal Transduction; GPCR Antibodies; Druggable G protein-coupled receptors (GPCRs)

Angiotensin II is a potent vasopressor hormone and aprimary regulator of aldosterone secretion. It is an importanteffector controlling blood pressure and volume in thecardiovascular system. It acts through at least two types ofreceptors. This gene encodes the type 1 receptor which is thoughtto mediate the major cardiovascular effects of angiotensin II. Thisgene may play a role in the generation of reperfusion arrhythmiasfollowing restoration of blood flow to ischemic or infarctedmyocardium. It was previously thought that a related gene, denotedas AGTR1B, existed; however, it is now believed that there is onlyone type 1 receptor gene in humans. At least five transcriptvariants have been described for this gene. Additional variantshave been described but their full-length nature has not beendetermined. The entire coding sequence is contained in the terminalexon and is present in all transcript variants. [provided byRefSeq].

RB19701

Affinity Purified Rabbit Polyclonal Antibody (Pab)

Pig, Rb

HUMAN

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Synthetic Peptide