INPP5B Antibody (C-term)

Synthetic Peptide

Cellular calcium signaling is controlled by the production
of inositol phosphates (IPs) by phospholipase C in response to
extracellular signals. The IP signaling molecules are inactivated
by a family of inositol polyphosphate-5-phosphatases
(5-phosphatases). INPP5B encodes the type II 5-phosphatase. The
protein is localized to the cytosol and mitochondria, and
associates with membranes through an isoprenyl modification near
the C-terminus. Several alternatively spliced transcript variants
of this gene have been described, but the full-length nature of
some of these variants has not been determined. [provided by
RefSeq].

Polyclonal

3633

Affinity Purified Rabbit Polyclonal Antibody (Pab)

Anti-INPP5B Antibody (C-term) at 1:1000 dilution + Daudi whole cell lysate

Lysates/proteins at 20 µg per lane.

Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.

Predicted band size : 113 kDa

Blocking/Dilution buffer: 5% NFDM/TBST.

1:1000

IHC-P

INPP5B Antibody (C-term) (Cat. #AP10490b) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

1:10~50

Rabbit Ig

950-979

This INPP5B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 950-979 amino acids from the C-terminal region of human INPP5B.