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ITGAE Antibody (C-term)

ArtNr ABC-AP10494b
Hersteller Abcepta
Menge 400 ul
Kategorie
Typ Antibody Polyclonal
Applikationen WB
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Citations Silva, L.K., et al. Eur. J. Hum. Genet. 18(11):1221-1227(2010)
Liu, Y.H., et al. Ophthalmology 117(8):1645-1651(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010):
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Heron, M., et al. Clin. Immunol. 133(1):117-125(2009)
NCBI NP_002199.3
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Integrin alpha-E,HML-1 antigen,Integrin alpha-IEL,Mucosal lymphocyte 1 antigen,CD103,Integrin alpha-E light chain,Integrin alpha-E heavy chain,ITGAE
Similar products ITGAE, CD103, HML-1 antigen, Integrin alpha-E, Integrin alpha-IEL, Mucosal lymphocyte 1 antigen, Integrin alpha-E heavy chain, Integrin alpha-E light chain
Lieferbar
Manufacturer - Category
Primary Antibodies; Immunology; Signal Transduction; Integrin Antibodies
Manufacturer - Targets
This ITGAE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1146-1173 amino acids from the C-terminal region of human ITGAE.
Bio Background
Integrins are heterodimeric integral membrane proteinscomposed of an alpha chain and a beta chain. ITGAE encodes anI-domain-containing alpha integrin that undergoespost-translational cleavage in the extracellular domain, yieldingdisulfide-linked heavy and light chains. In combination with thebeta 7 integrin, this protein forms the E-cadherin binding integrinknown as the human mucosal lymphocyte-1 antigen. This protein ispreferentially expressed in human intestinal intraepitheliallymphocytes (IEL), and in addition to a role in adhesion, it mayserve as an accessory molecule for IEL activation. [provided byRefSeq].
Clonality
Polyclonal
Polyclonal Antibody Additonal Information
RB27645
Gene Name
ITGAE
Subtitle
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Calculated Molecular Weight
130159
Antigen Source
HUMAN
Antigen Region
1146-1173
Formulation
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution
WB: 1:1000
Antigen Type
Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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