NKX2-1 Antibody (N-term)

P23441; P50220; NP_003308.1

This gene encodes a protein initially identified as a
thyroid-specific transcription factor. The encoded protein binds to
thyroglobulin promoter and regulates the expression of
thyroid-specific genes but has also been shown to regulate the
expression of genes involved in morphogenesis. Mutations and
deletions in this gene are associated with benign hereditary
chorea, choreoathetosis, congenital hypothyroidism, and neonatal
respiratory distress, and may be associated with thyroid cancer.
Multiple transcript variants encoding different isoforms have been
found for this gene.

7080

H, M

38596

HUMAN

NP_001073136.1; NP_003308.1