TNFRSF1A Antibody (N-term)

Primary Antibodies; Antibody Collections; Cancer; Cardiovascular; Cell Biology; Immunology; Signal Transduction; Amyotrophic Lateral Sclerosis (ALS); Viral process; Host-virus interaction; Apoptosis; Apoptosis signaling

The protein encoded by this gene is a member of theTNF-receptor superfamily. This protein is one of the majorreceptors for the tumor necrosis factor-alpha. This receptor canactivate NF-kappaB, mediate apoptosis, and function as a regulatorof inflammation. Antiapoptotic protein BCL2-associated athanogene 4(BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown tointeract with this receptor, and thus play regulatory roles in thesignal transduction mediated by the receptor. Germline mutations ofthe extracellular domains of this receptor were found to beassociated with the autosomal dominant periodic fever syndrome. Theimpaired receptor clearance is thought to be a mechanism of thedisease.

RB28843

Affinity Purified Rabbit Polyclonal Antibody (Pab)

50495

17-43

IF: 1:10~50
WB: 1:1000
IHC-P: 1:50~100
FC: 1:10~50

Tumor necrosis factor receptor superfamily member 1A, Tumor necrosis factor receptor 1, TNF-R1, Tumor necrosis factor receptor type I, TNF-RI, TNFR-I, p55, p60, CD120a, Tumor necrosis factor receptor superfamily member 1A, membrane form, Tumor necrosis factor-binding protein 1, TBPI, TNFRSF1A, TNFAR, TNFR1