MMP1 Antibody (Center)

Synthetic Peptide

Proteins of the matrix metalloproteinase (MMP) family are
involved in the breakdown of extracellular matrix in normal
physiological processes, such as embryonic development,
reproduction, and tissue remodeling, as well as in disease
processes, such as arthritis and metastasis. Most MMP's are
secreted as inactive proproteins which are activated when cleaved
by extracellular proteinases. This gene encodes a secreted enzyme
which breaks down the interstitial collagens, types I, II, and III.
The gene is part of a cluster of MMP genes which localize to
chromosome 11q22.3. Alternative splicing results in multiple
transcript variants.

Polyclonal

4312

Affinity Purified Rabbit Polyclonal Antibody (Pab)

Confocal immunofluorescent analysis of MMP1 Antibody (Center) (Cat#AP11874c) with MDA-MB231 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

1:10~50

WB

MMP1 Antibody (Center) (Cat. #AP11874c)immunohistochemistry analysis in formalin fixed and paraffin embedded human esophageal carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MMP1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

1:50~100

Rabbit Ig

317-347

This MMP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 317-347 amino acids from the Central region of human MMP1.