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TRADD Antibody (Center)

TRADD Antibody (Center)

ArtNr	ABC-AP11963c-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Antibodies Cell Biology Cell Status Apoptosis Flow Cytometry Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, FC, IF, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Pointon, J.J., et al. Ann. Rheum. Dis. 69(6):1243-1246(2010) Hosgood, H.D. III, et al. Occup Environ Med 66(12):848-853(2009) Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009) Liang, X.S., et al. Br. J. Haematol. 146(4):418-423(2009) Dagle, J.M., et al. Pediatrics 123(4):1116-1123(2009)
NCBI	NP_003780.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Tumor necrosis factor receptor type 1-associated DEATH domain protein,TNFR1-associated DEATH domain protein,TNFRSF1A-associated via death domain,TRADD
Similar products	TRADD, Tumor necrosis factor receptor type 1-associated DEATH domain protein, TNFRSF1A-associated via death domain, TNFR1-associated DEATH domain protein
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Manufacturer - Category	Primary Antibodies; Cancer; Cardiovascular; Cell Biology; Immunology; Signal Transduction; RIG-l-like Receptor; Apoptosis; Apoptosis signaling
Manufacturer - Targets	This TRADD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 126-151 amino acids from the Central region of human TRADD.
Bio Background	The protein encoded by this gene is a death domaincontaining adaptor molecule that interacts with TNFRSF1A/TNFR1 andmediates programmed cell death signaling and NF-kappaB activation.This protein binds adaptor protein TRAF2, reduces the recruitmentof inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thussuppresses TRAF2 mediated apoptosis. This protein can also interactwith receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and isinvolved in the Fas-induced cell death pathway. [provided byRefSeq].
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB18788
Gene Name	TRADD {ECO:0000303\|PubMed:7758105, ECO:0000312\|HGNC:HGNC:12030}
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Calculated Molecular Weight	34247
Antigen Source	HUMAN
Antigen Region	126-151
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	IF: 1:10~50 WB: 1:1000 IHC-P: 1:50~100 FC: 1:10~50
Antigen Type	Synthetic Peptide

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