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PCAF Antibody (N-term)

PCAF Antibody (N-term)

ArtNr	ABC-AP12074a-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen	WB
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	KAT2B, PCAF, Histone acetyltransferase KAT2B, Histone acetyltransferase PCAF, Lysine acetyltransferase 2B, P300/CBP-associated factor, P/CAF, Histone acetylase PCAF
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Primary Accession	Q92831
Antigen Type	Synthetic Peptide
Application	WB
Bio Background	CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.
Bio References	Perez, R.E., et al. J. Cell. Physiol. 225(2):394-405(2010) Mooney, S.M., et al. J. Biol. Chem. 285(40):30443-30452(2010) Aoyama, T., et al. J. Biol. Chem. 285(39):29842-29850(2010) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Shimahara, A., et al. J. Biol. Chem. 285(22):16967-16977(2010)
Clonality	Polyclonal
Clone/Animal Names	RB14383
Gene ID	8850
Gene Name	KAT2B {ECO:0000303\|PubMed:27796307, ECO:0000312\|HGNC:HGNC:8638}
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	PCAF Antibody (N-term) (Cat. #AP12074a) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the PCAF antibody detected the PCAF protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Other Accession	Q9JHD1; NP_003875.3
Predicted	M
Isotype	Rabbit Ig
Calculated MW	93013
Antigen Region	253-283
Antigen Source	HUMAN
Target/Specificity	This PCAF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 253-283 amino acids from the N-terminal region of human PCAF.
NCBI Accession	NP_003875.3

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Menge: 80 ul

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