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VEGFA Antibody (Center)

VEGFA Antibody (Center)

ArtNr	ABC-AP12184c
Hersteller	Abcepta
Menge	400 ul
Kategorie	Oncology Antibodies By Cell Type Carcinoma Cell Biology Cell Culture Cytokines Adenocarcinoma Western Blot Primary Antibodies By Organ Bladder Cancer
Typ	Antibody Polyclonal
Applikationen	WB
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Shrivastava-Ranjan, P., et al. J. Virol. 84(21):11227-11234(2010) Kim, Y.H., et al. Gynecol. Oncol. 119(2):232-236(2010) Yang, Y., et al. Exp. Biol. Med. (Maywood) 235(10):1204-1211(2010) Huez, I., et al. Mol. Endocrinol. 15(12):2197-2210(2001) Tee, M.K., et al. Biochem. J. 359 (PT 1), 219-226 (2001) :
NCBI	NP_001020537.2,NP_001020538.2,NP_001020539.2,NP_001020540.2,NP_001020541.2,NP_001028928.1,NP_001165093.1,NP_001165094.1,NP_001165095.1,NP_001165096.1,NP_001165097.1,NP_001165098.1,NP_001165099.1,NP_00
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Vascular endothelial growth factor A,VEGF-A,Vascular permeability factor,VPF,VEGFA,VEGF
Similar products	VEGF, VEGF-A, VEGFA, Vascular endothelial growth factor A, Vascular permeability factor, VPF
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Manufacturer - Category	Primary Antibodies; Cancer; Cardiovascular; Developmental Biology; Metabolism; Signal Transduction; Immune system process; Cystine-knot cytokines
Manufacturer - Targets	This VEGFA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140-168 amino acids from the Central region of human VEGFA.
Bio Background	This gene is a member of the PDGF/VEGF growth factorfamily and encodes a protein that is often found as a disulfidelinked homodimer. This protein is a glycosylated mitogen thatspecifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducingangiogenesis, vasculogenesis and endothelial cell growth, promotingcell migration, and inhibiting apoptosis. Elevated levels of thisprotein is linked to POEMS syndrome, also known as Crow-Fukasesyndrome. Mutations in this gene have been associated withproliferative and nonproliferative diabetic retinopathy.Alternatively spliced transcript variants, encoding either freelysecreted or cell-associated isoforms, have been characterized.There is also evidence for the use of non-AUG (CUG) translationinitiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB32234
Gene Name	VEGFA
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Calculated Molecular Weight	43597
Antigen Source	HUMAN
Antigen Region	140-168
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB: 1:1000
Antigen Type	Synthetic Peptide

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Menge: 400 ul

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