PSCD2 Antibody (N-term)

Synthetic Peptide

The protein encoded by this gene is a member of the PSCD
family. Members of this family have identical structural
organization that consists of an N-terminal coiled-coil motif, a
central Sec7 domain, and a C-terminal pleckstrin homology (PH)
domain. The coiled-coil motif is involved in homodimerization, the
Sec7 domain contains guanine-nucleotide exchange protein (GEP)
activity, and the PH domain interacts with phospholipids and is
responsible for association of PSCDs with membranes. Members of
this family appear to mediate the regulation of protein sorting and
membrane trafficking. The encoded protein exhibits GEP activity in
vitro with ARF1, ARF3, and ARF6 and is 83% homologous to CYTH1. Two
transcript variants encoding different isoforms have been found for
this gene.

Polyclonal

9266

Affinity Purified Rabbit Polyclonal Antibody (Pab)

PSCD2 Antibody (N-term) (Cat. #AP12239a) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the PSCD2 antibody detected the PSCD2 protein (arrow).

1:1000

B, Rat

46546

HUMAN

NP_004219.3; NP_059431.1