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AKR1C2 Antibody (C-term)

AKR1C2 Antibody (C-term)

Hersteller	Abcepta
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Specific against	other
Isotype	Ig
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB, IHC-P
Menge	400 ul
Host	Rabbit
ArtNr	ABC-AP12246B
eClass 6.1	32160702
eClass 9.0	32160702
Lieferbar
Primary Accession	P52895
Antigen Type	Synthetic Peptide
Application	WB, IHC-P
Bio Background	This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Bio References	Setlur, S.R., et al. Cancer Epidemiol. Biomarkers Prev. 19(1):229-239(2010) Wang, X., et al. PLoS ONE 5 (8), E11934 (2010) : Reding, K.W., et al. Am. J. Epidemiol. 170(10):1241-1249(2009) Cogliati, C., et al. FEBS J. 276(20):6011-6023(2009) Davies, N.J., et al. Cancer Res. 69(11):4769-4775(2009)
Clonality	Polyclonal
Clone/Animal Names	RB32249
Gene ID	1646
Gene Name	AKR1C2
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	All lanes : Anti-AKR1C2 Antibody (C-term) at 1:2000 dilution Lane 1: HepG2 whole cell lysate Lane 2: A549 whole cell lysate Lane 3: U-87 MG whole cell lysate Lane 4: Hela whole cell lysate Lane 5: COLO 205 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 37 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 1	WB
Dilution image 1	1:2000
Legend image 2	AKR1C2 Antibody (C-term) (Cat. #AP12246b)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of AKR1C2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:10~50
Other Accession	Q95JH7; Q04828; NP_995317.1
Predicted	Pr
Isotype	Rabbit Ig
Calculated MW	36735
Antigen Region	296-323
Antigen Source	HUMAN
Target/Specificity	This AKR1C2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-323 amino acids from the C-terminal region of human AKR1C2.
NCBI Accession	NP_001128713.1; NP_001345.1; NP_995317.1

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ABC-AP12246B-datasheet.pdf

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Menge: 400 ul

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Lieferung vsl. bis 04.07.2024

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