« Zurück
Startseite /
BCL2A1 (A1) Antibody (BH3 Domain Specific)

BCL2A1 (A1) Antibody (BH3 Domain Specific)

ArtNr	ABC-AP1300a
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen	WB, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	BCL2A1, BCL2L5, BFL1, GRS, HBPA1, Bcl-2-related protein A1, Bcl-2-like protein 5, Hemopoietic-specific early response protein, Protein BFL-1, Protein GRS, Bcl2-L-5
Lieferbar
Primary Accession	Q16548
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	Bcl-2 related Protein A1 is a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and has been shown to be up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival.
Bio References	Akatsuka, Y., et al., J. Exp. Med. 197(11):1489-1500 (2003). Edelstein, L.C., et al., Mol. Cell. Biol. 23(8):2749-2761 (2003). Werner, A.B., et al., J. Biol. Chem. 277(25):22781-22788 (2002). Akari, H., et al., J. Exp. Med. 194(9):1299-1311 (2001). Harrington, J.J., et al., Nat. Biotechnol. 19(5):440-445 (2001).
Clonality	Polyclonal
Clone/Animal Names	RB1251
Gene ID	597
Gene Name	BCL2A1
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of anti-Bcl2-related Protein A1 Pab (Cat. #AP1300a) in human placenta tissue lysate. Bcl2-related Protein A1 (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Type image 2	IHC-P
Dilution image 2	1:50~100
Isotype	Rabbit Ig
Calculated MW	20132
Antigen Region	30-65
Antigen Source	HUMAN
Target/Specificity	This BCL2A1 (A1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-65 amino acids from human BCL2A1 (A1).
NCBI Accession	NP_001108207.1; NP_004040.1

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

ABC-AP1300a-datasheet.pdf

Sicherheitsdatenblatt anfordern

Einfache Bestellung Periodische Bestellung

Menge: 400 ul

lieferbar

Lieferung vsl. bis 06.11.2025

Express-Lieferung: 1 Tage sparen

Vergleichen

Auf den Wunschzettel

Angebot anfordern