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REPS2 Antibody (N-term)

REPS2 Antibody (N-term)

ArtNr	ABC-AP13131a-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB, IHC-P
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	REPS2, POB1, RalBP1-associated Eps domain-containing protein 2, Partner of RalBP1, RalBP1-interacting protein 2
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Primary Accession	Q8NFH8
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	The product of this gene is part of a protein complex that regulates the endocytosis of growth factor receptors. The encoded protein directly interacts with a GTPase activating protein that functions downstream of the small G protein Ral. Its expression can negatively affect receptor internalization and inhibit growth factor signaling. Multiple transcript variants encoding different isoforms have been found for this gene.
Bio References	Doolan, P., et al. Tumour Biol. 30(4):200-209(2009) Singhal, S.S., et al. J. Biol. Chem. 283(28):19714-19729(2008) Yadav, S., et al. Biochem. Biophys. Res. Commun. 328(4):1003-1009(2005) Oosterhoff, J.K., et al. Int. J. Cancer 113(4):561-567(2005) Penninkhof, F., et al. Oncogene 23(33):5607-5615(2004)
Clonality	Polyclonal
Clone/Animal Names	RB32411
Gene ID	9185
Gene Name	REPS2
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Legend image 1	REPS2 Antibody (N-term) (Cat. #AP13131a) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the REPS2 antibody detected the REPS2 protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	REPS2 Antibody (N-term) (Cat. #AP13131a)immunohistochemistry analysis in formalin fixed and paraffin embedded human cerebellum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of REPS2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:10~50
Other Accession	NP_004717.2; NP_001074444.1
Isotype	Rabbit Ig
Calculated MW	71534
Antigen Region	153-182
Antigen Source	HUMAN
Target/Specificity	This REPS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 153-182 amino acids from the N-terminal region of human REPS2.
NCBI Accession	NP_001074444.1; NP_004717.2

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Menge: 80 ul

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