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CASP10 Antibody (Center)

ArtNr ABC-AP1326c-ev
Hersteller Abcepta
Menge 80 ul
Kategorie
Typ Antibody Polyclonal
Applikationen WB
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Citations Lan,Q., Morton,L.M. Blood 114 (2), 264-267 (2009)
Kim,Y.R., Kim,K.M. Hum. Pathol. 40 (6), 868-871 (2009)
Lisa-Santamaria,P. Biochim. Biophys. Acta 1793 (3), 561-571 (2009)
NCBI NP_001193453.1,NP_001193471.1,NP_001221.2,NP_116756.2,NP_116758.1,NP_116759.2
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Caspase-10,CASP-10,Apoptotic protease Mch-4,FAS-associated death domain protein interleukin-1B-converting enzyme 2,FLICE2,ICE-like apoptotic protease 4,Caspase-10 subunit p23/17,Caspase-10 subunit p12,CASP10,MCH4
Similar products Caspase-10, CASP10, FLICE2, MCH4, ICE-like apoptotic protease 4, Apoptotic protease Mch-4, CASP-10, FAS-associated death domain protein interleukin-1B-converting enzyme 2, Caspase-10 subunit p12, Caspase-10 subunit p23/17
Lieferbar
Manufacturer - Category
Primary Antibodies; Cancer; Cell Biology; Metabolism; RIG-l-like Receptor; Apoptosis; Apoptosis signaling
Manufacturer - Targets
This CASP10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 164-192 amino acids from the Central region of human CASP10.
Bio Background
CASP1 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in the protein are associated with apoptosis defects seen in type II autoimmune lymphoproliferative syndrome.
Clonality
Polyclonal
Polyclonal Antibody Additonal Information
RB18398
Gene Name
CASP10
Subtitle
Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Calculated Molecular Weight
58951
Antigen Source
HUMAN
Antigen Region
164-192
Formulation
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Dilution
WB: 1:1000
Antigen Type
Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 80 ul
Lieferbar: In stock
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