IL13 Antibody (C-term)

Primary Antibodies; Cancer; Immunology; Signal Transduction; Cytokine; Jak-STAT signaling KEGG

This gene encodes an immunoregulatory cytokine producedprimarily by activated Th2 cells. This cytokine is involved inseveral stages of B-cell maturation and differentiation. Itup-regulates CD23 and MHC class II expression, and promotes IgEisotype switching of B cells. This cytokine down-regulatesmacrophage activity, thereby inhibits the production ofpro-inflammatory cytokines and chemokines. This cytokine is foundto be critical to the pathogenesis of allergen-induced asthma butoperates through mechanisms independent of IgE and eosinophils.This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster onchromosome 5q, with this gene particularly close to IL4. [providedby RefSeq].

RB33718

Affinity Purified Rabbit Polyclonal Antibody (Pab)

15788

118-146

IF: 1:10~50
WB: 1:1000
IHC-P: 1:10~50